Our Capabilities

Protein Structure and Biophysics

The Protein Structure & Biophysics (PSB) platform supports the determination of high-resolution structures of proteins and protein-ligand complexes. Over the years, the group has solved a large number of protein-compound co-structures allowing structure-based design and accelerating the discovery process. The projects tackled by the team cover a wide variety of target classes. PSB also works with the large molecule projects for epitope mapping and to better understand the antibody-antigen interactions.

Key expertise:

  • Protein construct design and optimization
  • Protein expression and purification
  • Crystallization screens and crystals optimization
  • Protein-ligand complex analysis

This capability is also available on a fee-for-service basis, please refer to www.earo.sg.